Obesity is a chronic metabolic disorder that affects half a billion people worldwide. Managing obesity is difficult, as many patients rebound to their pre-treatment weight. There is a hypothesis that chronic weight gain causes the body to adopt a state that supports excess weight.
URL: http://www.news-medical.net/news/20121025/Pomc-gene-can-be-turned-on-and-off-in-a-mouse-model-of-obesity.aspx
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