Australian scientists have shown how a 'transcription factor' causes breast cancer to develop an aggressive subtype that lacks sensitivity to oestrogen and does not respond to anti-oestrogen therapies such as Tamoxifen and aromatase inhibitors.
URL: http://www.news-medical.net/news/20121228/Manipulating-transcription-factor-can-change-subtype-of-breast-cancer.aspx
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